• Pulmonary manifestations and progression of lung disease in juvenile-onset mixed connective tissue disease 

      Hetlevik, Siri Opsahl; Flatø, Berit; Aaløkken, Trond Mogens; Samersaw-Lund, May Brit; Reiseter, Silje; Mynarek, Georg; Nordal, Ellen Berit; Rygg, Marite; Lilleby, Vibke (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-01)
      <i>Objective</i> - To assess the occurrence and extent of interstitial lung disease (ILD) in patients with juvenile mixed connective tissue disease (JMCTD), compare pulmonary function in patients and matched controls, study associations between ILD and disease-related variables, and examine progression of pulmonary manifestations over time.<p> <p><i>Methods</i> - A cohort of 52 patients with JMCTD ...
    • A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis 

      Sikkeland, Liv Ingunn Bjoner; Ueland, Thor; Samersaw-Lund, May Brit; Durheim, Michael Thomas; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-09)
      Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease characterized by damage to the alveolar epithelium, leading to fibrosis and excessive accumulation of extracellular matrix in the interstitium of the lung. In the present study we performed high-resolution proteomic profiling of bronchoalveolar lavage (BAL) from IPF patients and controls, and found that the ...